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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-24-357534 |
AM06040PU-N |
JAB1 / COPS5//Human, Mouse/Mouse |
1/EA |
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Subject
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JAB1 / COPS5 |
Description
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/ Human, Mouse/Mouse |
Clonality
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Mono |
Company
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Acris Antibodies GmbH |
Application
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Immunofluorescence, Paraffin Sections, Western blot / Immunoblot, Immunoprecipitation |
Conjugation
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Immunogen
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Contents
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Description: Manufacturer | Acris Antibodies GmbH | Quantity | 50 ug | Reactivity | Human, Mouse | Presentation | Purified | Applications | Immunofluorescence, Paraffin Sections, Western blot / Immunoblot, Immunoprecipitation | Isotype | IgG2b | Host | Mouse | Clone | 2A10.8 | PDF datasheet | view | Shipping to | Not USA/Canada | Synonyms | COPS5, CSN5, 38 Kda Mov34 Isologue, JAB-1, MGC3149, MOV-34, SGN5 | Swiss Prot Num | Q92905 | Immunogen | Recombinant full-length mouse JAB-1 gene expressed in E. coli. | Product Type | Antibodies | Recommended Isotype Control | SM12P, AM03110PU-N | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | |
Format | State: Liquid purified Ig fraction. | ? | Purification: Protein G Chromatography. | ? | Buffer System: PBS, pH 7.4 without preservatives. | |
Specificity | This antibody detects 38 Kda Mov34 Isologue (COPS5). | Application | Immunoprecipitation. Immunoflourescence. Western blot. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100°C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. | Background | JAB-1 is a 38 kDa protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the "Signalosome", which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome. | Concentration | 1.0 mg/ml | |
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