Synonyms | Jumonji/ARID domain-containing protein 1A; Retinoblastoma-binding protein 2; RBBP-2; JARID1A; RBBP2; RBP2;; KDM5A |
Swiss Prot Num | P29375 |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from N-terminal region of human JARID1A. |
Product Type | Antibodies |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
References | 1. Mao, S., et al., Oncogene 14(13):1531-1539 (1997). 2. Baens, M., et al., Genomics 29(1):44-52 (1995). 3. Fattaey, A.R., et al., Oncogene 8(11):3149-3156 (1993). 4. Defeo-Jones, D., et al., Nature 352(6332):251-254 (1991). |
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Format | State: Liquid purified Ig fraction. |
? | Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
? | Buffer System: PBS containing 0.09% (W/V) Sodium Azide as preservative. |
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Specificity | This antibody is specific to JARID1A (N-term). |
Application | ELISA: 1/1,000. |
Background | The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein. |
Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Concentration | 0.25 mg/ml |