| Synonyms | JmjC domain-containing histone demethylation protein 1A; [Histone-H3]-lysine-36 demethylase 1A; F-box/LRR-repeat protein 11; F-box and leucine-rich repeat protein 11; F-box protein FBL7; F-box protein Lilina; CXXC-type zinc finger protein 8; FBXL11 |
| Swiss Prot Num | Q9Y2K7 |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the Center of human JHDM1a/FBXL11. |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Tsukada,Y.,Nature 439 (7078), 811-816 (2006) 2. Andersen,J.S.,Nature 433 (7021), 77-83 (2005) |
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| Format | State: Liquid purified Ig fraction. |
| ? | Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| ? | Buffer System: PBS containing 0.09% (W/V) Sodium Azide as preservative. |
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| Specificity | This antibody is specific to JHDM1a/FBXL11 (Center). Predicted to cross react with Mouse (100% Antigen Homology). |
| Application | ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemsitry: 1/10~1/50. |
| Background | JHDM1a/FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats. |
| Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Concentration | 0.25 mg/ml |
