Synonyms | JMJD2A; JHDM3A, JMJD2, KIAA0677 |
Swiss Prot Num | O75164 |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human JMJD2A. |
Product Type | Antibodies |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
References | 1. Gray S.G., Iglesias A.H.J. Biol. Chem. 280:28507-28518(2005) 2. Zhang D., Yoon H.-G.Mol. Cell. Biol. 25:6404-6414(2005) 3. Whetstine J.R., Nottke A.Cell 125:467-481(2006) |
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Format | State: Liquid purified Ig fraction. |
? | Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
? | Buffer System: PBS containing 0.09% (W/V) Sodium Azide as preservative. |
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Specificity | This antibody is specific to JMJD2A (N-term). |
Application | ELISA: 1/1,000. Western Blot: 1/50-1/100. |
Background | JMJD2A is a member of the Jumonji domain 2 (JMJD2) family and a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. |
Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Concentration | 0.25 mg/ml |