| Synonyms | KLK-1, EC 3.4.21.35, Tissue kallikrein, FocusOn006 |
| Swiss Prot Num | P06870 |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human KLK1. |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Montanari, D., et al., Diabetes 54(5):1573-1580 (2005). 2. Yin, H., et al., J. Biol. Chem. 280(9):8022-8030 (2005). 3. Azizi, M., et al., J. Clin. Invest. 115(3):780-787 (2005). 4. Lee-Chen, G.J., et al., Kidney Int. 65(4):1467-1472 (2004). 5. Casalino-Matsuda, S.M., et al., J. Biol. Chem. 279(20):21606-21616 (2004). |
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| Format | State: Liquid purified Ig |
| ? | Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
| ? | Buffer System: PBS with 0.09% (W/V) sodium azide |
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| Specificity | This antibody reacts to Kallikrein 1 (KLK1). |
| Application | ELISA: 1/1,000. |
| Background | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK1 is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. |
| Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Concentration | 0.25 mg/ml |
| Focuson | 006 Antibodies to Kallikrein Family |
