Synonyms | KLK-10, NES1, PRSSL1, Protease serine-like 1, FocusOn006 |
Swiss Prot Num | O43240 |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human KLK10. |
Product Type | Antibodies |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
References | 1. Diamandis, E.P., et al., Clin. Biochem. 37(3):230-237 (2004). 2. Sauter, E.R., et al., Int. J. Cancer 108(4):588-591 (2004). 3. Petraki, C.D., et al., Prostate Cancer Prostatic Dis. 6(3):223-227 (2003). 4. Luo, L.Y., et al., Br. J. Cancer 86(11):1790-1796 (2002). 5. Bharaj, B.B., et al., Prostate 51(1):35-41 (2002). |
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Format | State: Liquid purified Ig |
? | Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
? | Buffer System: PBS with 0.09% (W/V) sodium azide |
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Specificity | This antibody reacts to Kallikrein 10 (KLK10). |
Application | ELISA: 1/1000. |
Background | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene for KLK10 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. |
Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Concentration | 0.25 mg/ml |
Focuson | 006 Antibodies to Kallikrein Family |