Synonyms | KLK-15, ACO Protease, FocusOn006 |
Swiss Prot Num | Q9H2R5 |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human KLK15. |
Product Type | Antibodies |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
References | 1. Yousef, G.M., et al., J. Clin. Oncol. 21(16):3119-3126 (2003). 2. Yousef, G.M., et al., Br. J. Cancer 87(11):1294-1300 (2002). 3. Diamandis, E.P., et al., Expert Rev Mol Diagn 1(2):182-190 (2001). 4. Takayama, T.K., et al., Biochemistry 40(6):1679-1687 (2001). 5. Yousef, G.M., et al., J. Biol. Chem. 276(1):53-61 (2001). |
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Format | State: Liquid purified Ig |
? | Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
? | Buffer System: PBS with 0.09% (W/V) sodium azide |
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Specificity | This antibody reacts to KLK15. |
Application | ELISA: 1/1,000. Western blotting: 1/100 - 1/500. |
Background | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In prostate cancer, KLK15 has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. |
Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Concentration | 0.25 mg/ml |
Focuson | 006 Antibodies to Kallikrein Family |