Synonyms | Serine protease 17, Prostase, KLK-4, KLK-L1, EMSP1, PRSS17, PSTS, FocusOn006 |
Swiss Prot Num | Q9Y5K2 |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human KLK4. |
Product Type | Antibodies |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
References | 1. Hart, P.S., et al., J. Med. Genet. 41(7):545-549 (2004). 2. Xi, Z., et al., Cancer Res. 64(7):2365-2370 (2004). 3. Hural, J.A., et al., J. Immunol. 169(1):557-565 (2002). 4. Takayama, T.K., et al., Biochemistry 40(50):15341-15348 (2001). 5. Korkmaz, K.S., et al., DNA Cell Biol. 20(7):435-445 (2001). |
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Format | State: Liquid purified Ig |
? | Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS |
? | Buffer System: PBS with 0.09% (W/V) sodium azide |
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Specificity | This antibody reacts to Kallikrein 4 (KLK4). |
Application | ELISA: 1/1,000. |
Background | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In some tissues KLK4 expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. |
Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Concentration | 0.25 mg/ml |
Focuson | 006 Antibodies to Kallikrein Family |