| Synonyms | KLK-6, PRSS18, PRSS9, Protease M, Neurosin, Zyme, SP59, FocusOn006 |
| Swiss Prot Num | Q92876 |
| Immunogen | Recombinant human kallikrein 6 |
| Product Type | Antibodies |
| Recommended Isotype Control | SM10P (for use in human samples), AM03095PU-N |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Diamandis, E. P. et al. (2001) The spectrum of human kallikrein 6 (zyme protease m/neurosin) expression in human tissues, as assessed by immunohistochemistry. J. Histochem. Cytochem. 49: 1431 - 1441. 2. Diamandis, E. P. et al. (2000) Human kallikrein 6 as a biomarker of alzheimer's disease. Clin. Biochem. 33: 663 - 667. 3. Ogawa. K. et al. (2000) Localization of a novel type trypsin-like serine protease, neurosin, in brain tissues of Alzheimer's disease and Parkinson's disease. Psychiatry Clin. Neurosci. 54: 419 - 426. |
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| Format | State: Liquid purified IgG |
| ? | Buffer System: Phosphate buffered saline containing 0.09% Sodium Azide |
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| Specificity | This antibody recognises kallikrein 6, a serine protease of 30kD. |
| Application | Immunohistochemistry on paraffin sections: 1/50 - 1/100; This product does not require protein digestion pre-treatment of paraffin sections. Immunohistochemistry on frozen sections. |
| Background | Kallikrein 6 is broadly expressed in glandular epithelia. In the brain the molecule has been located in the epithelial cells of the choroid plexus. Soluble kallikrein 6 has also recently been reported as a potential marker for Alzheimer's disease, with blood levels being increased significantly over controls. |
| Caution | (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. |
| Concentration | 1.0 mg/ml. |
| Focuson | 006 Antibodies to Kallikrein Family |
