| Catalog Number | GTX28993 |
| Product Name | E Cadherin [MB2] antibody |
| Product Description | Mouse monoclonal [MB2] to E Cadherin |
| Synonyms | 999 | CDH1 | 137215 | P12830 | Arc-1 | CDHE | ECAD | LCAM | UVO | |
| Background | Cadherins constitute a family of proteins, the members of which are differentially expressed in the different tissues. One of the best characterized members is E-cadherin, which is prevalent in epithelial tissues. It has been shown to play a crucial role in the process of tumor cell metastasis. |
| Clonality | Monoclonal |
| Clone No | MB2 |
| Host | Mouse |
| Isotype | IgG2b |
| Immunogen | MCF-7/AZ cells expressing E-Cadherin at their cell surface |
| Tested Applications | Flow cytometry/FACS, Immunocytochemistry, IHC (Frozen sections), Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | FACS: 1/100 - 1/200. ICC: Use at an assay dependent dilution. IHC-Fr: Use at an assay dependent dilution. WB: 1/100 - 1/1000. |
| Specificity | Specific reactivity with 120 kDa protein and its 80 kDa trypsin-resistant extracellular part |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Target | E Cadherin |
| Purification | Protein A affinity purified. |
| Storage Buffer | PBS, 0.09% Sodium Azide |
| Storage Instruction | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
