Product Type | Antibodies |
Recommended Isotype Control | SM10R (for use in human samples) |
Storage | Store the antibody in the dark at 2-8°C. Do Not Freeze! Avoid prolonged exposure to light. Shelf life: One year from despatch. |
References | 1. Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95. |
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Format | State: Liquid purified Ig fraction. |
? | Label: Cconjugated with R-Phycoerythrin (PE) under optimum conditions. |
? | Purification: Size-exclusion chromatography. |
? | Buffer System: PBS containing 15 mM sodium azide as preservative and 0.2% (w/v) high-grade BSA (Protease free) as stabilizer. |
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Specificity | This antibody reacts with kappa light chains (22.5 kDa) of immunoglobulins. Negative Species: Hamster, Sheep, Goat, Rabbit, Guinea pig |
Application | Suitable for Flow Cytometry analysis of human blood cells using 20 ?¨ùl reagent / 100 ?¨ùl of whole blood or 10e6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. |
Background | Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda; both having a molecular weight of 22.5kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. |