Synonyms | "Death-associated protein kinase 1, DAP kinase 1" |
Swiss Prot Num | P53355 |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human DAPK1. |
Product Type | Antibodies |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
References | 1. Shohat, G., et al., J. Biol. Chem. 276(50):47460-47467 (2001). 2. Inbal, B., et al., Mol. Cell. Biol. 20(3):1044-1054 (2000). 3. Deiss, L.P., et al., Genes Dev. 9(1):15-30 (1995). |
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Format | State: Liquid purified Ig |
? | Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS |
? | Buffer System: PBS with 0.09% (W/V) sodium azide |
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Specificity | This antibody reacts to DAP Kinase 1 (DAPK1). |
Application | ELISA: 1/1,000. |
Background | Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death (apoptosis). DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. |
Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Concentration | 0.25 mg/ml |