|
| |
| Cat. No |
Model |
Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-370178 |
NBP1-19355 |
E Cadherin 1/2/3/4 Antibody//Human, Mouse,/Rabbit |
1/EA |
|
|
|
|
문의 |
|
|
|
|
|
|
|
Subject
|
E Cadherin 1/2/3/4 Antibody |
|
Description
|
/ Human, Mouse,/Rabbit |
|
Clonality
|
Poly |
|
Company
|
Novus biologicals |
|
Application
|
IF, IHC-P, Western Blot |
|
Conjugation
|
|
|
Immunogen
|
|
|
Contents
|
Description:Summary: | Species: | Rt, Mu, Hu | | Applications: | IF, IHC, WB | | Clonality: | Polyclonal | | | Gene: | CDH1 | | Purity: | Affinity purified | | Host: | Rabbit | | | Specificity: | E- Cadherin1/2/3/4(R868) detects endogenous levels of E-Cadherin1/2/3/4 protein. | Details: Gene Symbol: CDH1 | Entrez: | 999 (Human) | | | 83502 (Rat) | | Related Genes: | CTNNB1, CTNNA1, APC, CDKN2A, PROC, TP53, SLC22A3, ITK, EGFR, VIM, JUP, FZR1, HGF, TJP1, ERBB2, CD44, VEGFA, MMP9, AKT1, RASSF1, MLH1, CCND1, EGF, CDKN1A, OCLN, CTNND1, PIK3CG, GSTP1, MGMT, PCNA, MYC, BCL2, SUB1, SNAI2, CDKN2B, IL6, CDC20, SRC, MMP-2, MMP2 | Background: Cadherins are members of a multigene family of single chain glycoprotein receptors mediating calcium dependent cell-cell adhesion. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherins are expressed in a tissue specific manner and and are required for assembly of cells into solid tissue. Individual cadherin molecules are known to co-operate with each other to form a linear cell adhesion zipper. In adhesion junctions cadherins are bound to beta and gamma catenins which in turn bind to alpha catenin, an actin binding protein. Cadherins play an important part in tumor invasion and metastasis. Species: | Reactivity: | Human, Mouse, Rat | Applications: | Uses: | This antibody is useful for Western Blot, Immunohistochemistry and Immunofluorescence.Western blot analysis of Cadherin1/2/3/4 (R868) antibody in extracts from NIH/3T3 cells.Immunohistochemistry analyzes of Cadherin1/2/3/4 (R868) antibody in paraffin-embedded human breast carcinoma tissue. | | Dilutions: | Western Blot 1:500-1:1000,immunohistochemistry 1:50-1:200,immunofluorescence 1:100-1:500, | Packaging: | Buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
|
|
|
|
