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| Cat. No |
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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-370180 |
NB100-91740 |
E Cadherin Antibody//Human/Rabbit |
1/EA |
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문의 |
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Subject
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E Cadherin Antibody |
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Description
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/ Human/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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ELISA, IF, IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Hu | | Applications: | IF, IHC, WB, ELISA | | Clonality: | Polyclonal | | | Gene: | CDH1 | | Purity: | Immunogen affinity purified | | Host: | Rabbit | | | Specificity: | E-cadherin(G2) detects endogenous levels of E-cadherin protein. | Details: Gene Symbol: CDH1 | Entrez: | 999 (Human) | | Related Genes: | CTNNB1, CTNNA1, APC, CDKN2A, PROC, TP53, SLC22A3, ITK, EGFR, VIM, JUP, FZR1, HGF, TJP1, ERBB2, CD44, VEGFA, MMP9, AKT1, RASSF1, MLH1, CCND1, EGF, CDKN1A, OCLN, CTNND1, PIK3CG, GSTP1, MGMT, PCNA, MYC, BCL2, SUB1, SNAI2, CDKN2B, IL6, CDC20, SRC, MMP-2, MMP2 | Background: One of the epithelial cell adhesion molecules, E Cadherin, plays an important role in the formation of cell-cell contacts in epithelia irrespective their origin form ecto-, meso- or endodermal tissue. This early adhesion event between epithelial cells is a prerequisite for the assembly of all elements of the junctional complex. Furthermore, E Cadherin plays a crucial role in the maintenance of the epithelial junctional complex and is as such an important molecule in maintaining epithelial integrity. Over 90% of the malignant tumors are carcimomas. One of the prerequisites for the release of carcinoma cells from the primary site might be a defect in intercellular adhesion mediated by the absence of E Cadherin expression. Therefore, the expression of E Cadherin might be an important parameter for the determination of the invasive potential of epithelial neoplasms, and for the transition of a benign to a malignant neoplasm. Species: Applications: | Uses: | ELISA, Western Blot, Immunohistochemistry and Immunofluorescence | | Dilutions: | ELISA 1:40000-1:60000, Western Blot 1:500-1:1000, immunohistochemistry 1:50-1:200, immunofluorescence, | | Concentrations: | 1.0 mg/ml | | Positive Controls: | 1 positive controls | Packaging: | Buffer: | Phosphate buffered saline, pH 7.2. | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | 15mM Sodium Azide | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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