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| Cat. No |
Model |
Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-370184 |
NBP1-04701 |
E Cadherin Antibody//Human, Mouse,/Chicken |
1/EA |
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문의 |
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Subject
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E Cadherin Antibody |
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Description
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/ Human, Mouse,/Chicken |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Mu, Hu | | Applications: | WB | | Clonality: | Polyclonal | | | Gene: | CDH1 | | Purity: | Affinity purified | | Host: | Chicken | | | Specificity: | E-cadherin | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Immunogen: | This polyclonal antibody was raised by immunizing chicken with E-cadherin fusion protein (441-523 amino acids). | Gene Symbol: CDH1 | Entrez: | 999 (Human) | | | 12550 (Mouse) | | | 83502 (Rat) | | Related Genes: | CTNNB1, CTNNA1, APC, CDKN2A, PROC, TP53, SLC22A3, ITK, EGFR, VIM, JUP, FZR1, HGF, TJP1, ERBB2, CD44, VEGFA, MMP9, AKT1, RASSF1, MLH1, CCND1, EGF, CDKN1A, OCLN, CTNND1, PIK3CG, GSTP1, MGMT, PCNA, MYC, BCL2, SUB1, SNAI2, CDKN2B, IL6, CDC20, SRC, MMP-2, MMP2 | Background: E-cadherin is a classical cadherin from the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. Species: | Reactivity: | Reacts with Human, Mouse and Rat. | Applications: | Uses: | Western blotting, tissue or cell immunostaining. Recommended starting dilution for Western blot analysis is 1:500, for tissue or cell staining is 1:200. | | Dilutions: | Western Blot | Packaging: | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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