|
| |
| Cat. No |
Model |
Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-366883 |
AP05767PU-N |
14-3-3 protein pan//Human, Mouse, Rat, Bovine, Canine, Chicken, Monkey/Rabbit |
1/EA |
|
|
|
 |
문의 |
|
|
|
|
|
|
|
Subject
|
14-3-3 protein pan |
|
Description
|
/ Human, Mouse, Rat, Bovine, Canine, Chicken, Monkey/Rabbit |
|
Clonality
|
Mono |
|
Company
|
Acris Antibodies GmbH |
|
Application
|
Western blot / Immunoblot |
|
Conjugation
|
|
|
Immunogen
|
|
|
Contents
|
Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 0.1 ml | | Reactivity | Human, Mouse, Rat, Bovine, Canine, Chicken, Monkey, Xenopus, Zebrafish | | Presentation | Purified | | Applications | Western blot / Immunoblot | | Isotype | IgG | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | YWHA, FocusOn116 | | Immunogen | Peptide corresponding to amino acid residues from the C-terminal region of the 14-3-3 protein, conjugated to keyhole limpet hemocyanin (KLH). | | Product Type | Antibodies | | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | | References | 1. Dougherty, M. K. and Morrison, D. K. (2004) Unlocking the code of 1433. J. Cell Sci. 117:1875 - 84. | |
| Format | State: Liquid purified IgG | | ? | Buffer System: 10mM Hepes pH7.5, 150mM NaCl containing 0.09% Sodium Azide (NaN3), 50% Glycerol 0.01% Bovine Serum Albumin | |
| Specificity | This antibody recognises 14-3-3 protein, a highly conserved, ubiquitously expressed protein family. | | Application | Western Blot: 1:1000; detects a band of approximately 29kDa in rat hippocampal lysate. | | Background | 14-3-3 proteins form homo- and heterodimers that can interact with a variety of cellular proteins that are typically phosphorylated on serine or threonine residues. 14-3-3 proteins regulate cellular processes such as trafficking, cell-cycle regulatory pathways and signal transduction. Brain tissue contains the highest concentration of 14-3-3 proteins and the proteins have been found in the cerebral spinal fluid of patients with certain neurodegenerative disease such as Creutzfeldt-Jakob disease and scrapie. 14-3-3 proteins might also contribute to Alzheimers and Parkinsons diseases, MillerDieker syndrome and spinocerebellar ataxia type 1. 14-3-3 has also been implicated in cancer. | | Caution | (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. | | Focuson | 116 Antibody Panel to Proteins of the 14-3-3 family (14-3-3 beta, 14-3-3 gamma, 14-3-3 epsilon, 14-3-3 zeta, 14-3-3 theta, 14-3-3 sigma, 14-3-3 eta) | |
|
|
|
|
