| Synonyms | S100-A1, S100A, S100A1 |
| Swiss Prot Num | P23297 |
| Immunogen | Recombinant protein encoding human S100 protein |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch. |
|
| Format | State: Liquid purified Ig |
| ? | Buffer System: 10mM PBS, pH 7.4 with BSA and Sodium Azide |
|
| Specificity | This antibody reacts to S100. |
| Application | Immunohistochemistry on paraffin sections (1:100 for 10min at RT. Positive Control: Melanoma or Schwannoma. |
| Background | S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. Antibody to S100 stains Schwannomas, ependymomas, astrogliomas, almost all benign and malignant melanomas and their metastases. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes. |
