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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-23-370286 |
H00001870-B01P |
E2F2 Antibody//Human/Mouse |
1/EA |
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¹®ÀÇ |
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Subject
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E2F2 Antibody |
Description
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/ Human/Mouse |
Clonality
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Poly |
Company
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Novus biologicals |
Application
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ELISA, Western Blot |
Conjugation
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Immunogen
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Contents
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Description:Summary: Protein Type: | Full length Protein | Species: | Hu | Applications: | ELISA, WB | Clonality: | Polyclonal | | Gene: | E2F2 | Purity: | protein A purified | Host: | Mouse | | Specificity: | E2F2 - E2F transcription factor 2, | Details: Immunogen: | E2F2 (AAH07609, 1 a.a. ~ 84 a.a) full-length human protein. | Epitope: | MESRSVAQAGVQWPDLGSLQPLPPRF KRFFCLSLQSSWDYRHAPPRPANFVF LVETGFCHVSQAGLELLTSSDPPPRP PKVLR* | Gene Symbol: E2F2 Entrez: | 1870 (Human) | Swiss Prot: | AAH07609 (Human) | Related Genes: | E2F1, E2F3, E2F4, E2F5, ARID4A, CDKN2A, RBL1, RBL2, CDKN1A, TFDP1, NOLC1, RAB3GAP1, TP53, MYC, RB1, CDK2, CDK4, CCNA2, CCND1, TCEAL1, D4S234E, NOL3, DHFR, PCNA, DAND5, SLC12A9, PSG1, SP1, TP53BP2, PAK3, E2F6, CCND3, POLD1, MDM2, CDC2, TP73, BCL2, MYCN, PTGDR, REEP5 | Background: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. [provided by RefSeq] Species: Applications: Uses: | Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. | Dilutions: | Western Blot 1:500,ELISA | Notes: This product is produced by and distributed for Abnova, a company based in Taiwan. Packaging: Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. | Preservative: | No Preservative | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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