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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-24-358524 |
AP07669PU-N |
NAIP//Human/Rabbit |
1/EA |
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¹®ÀÇ |
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Subject
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NAIP |
Description
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/ Human/Rabbit |
Clonality
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Mono |
Company
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Acris Antibodies GmbH |
Application
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Immunofluorescence, Paraffin Sections, Western blot / Immunoblot |
Conjugation
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Immunogen
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Contents
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Description: Manufacturer | Acris Antibodies GmbH | Quantity | 50 ug | Reactivity | Human | Presentation | Aff - Purified | Applications | Immunofluorescence, Paraffin Sections, Western blot / Immunoblot | Host | Rabbit | PDF datasheet | view | Shipping to | Not USA/Canada | Synonyms | BIRC1 | Swiss Prot Num | Q13075 | Immunogen | Synthetic peptide corresponding to 13 amino acids at the C-terminus of human NAIP. | Product Type | Antibodies | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C to -70°C for longer. Dilute only prior to immediate use. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | |
Format | State: Liquid purified IgG fraction. | ? | Purification: Immunoaffinity Chromatography. | ? | Buffer System: Phosphate Buffered Saline PBS, containing 0.02% Sodium Azide as preservative. | |
Specificity | Species Human. | Application | Immunohistochemistry on Paraffin Sections (5 ?g/ml). Immunocytochemistry. Western Blot (0.5-1 ?g/ml). | Background | Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy. Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR); these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules. Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO, suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported. | Concentration | 1.0 mg/ml | |
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