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Description |
Unit |
Price
(VAT별도) |
납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-23-353502 |
NBP1-07130 |
Apelin Antibody//Bovine, Human/Rabbit |
1/EA |
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문의 |
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Subject
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Apelin Antibody |
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Description
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/ Bovine, Human/Rabbit |
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Clonality
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Poly |
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Company
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Novus biologicals |
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Application
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IHC-P, Western Blot |
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Conjugation
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Immunogen
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Contents
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Description:Summary: | Species: | Rt, Mu, Hu, Bv | | Applications: | WB, IHC | | Clonality: | Polyclonal | | | Gene: | APLN | | Purity: | Whole antisera | | Host: | Rabbit | | | Specificity: | Reacts specifically with 8,5 kDa of human APLN protein | | Publications: | Antibody has not yet been mentioned in a publication. | Details: | Immunogen: | Synthetic peptide derived from C terminal region of human Apelin | Gene Symbol: APLN | Entrez: | 8862 (Human) | | | 30878 (Mouse) | | | 58812 (Rat) | | Related Genes: | APLNR, INS, NAMPT, AGT, AVP, AKT1, LEP, ADIPOQ, PIK3CG, RETN, HIF1A, TNF, VEGFA, IFNAR1, NLRP3, CD4, CCK, NOS3, POMC, MAPK3, ANG, PKC, MAPK1, TDGF1, VWF, IL6, GPR151, MRGPRX1, ANGPTL4, SERPINA12, LGR6, OXER1, SERPINE1, VN1R17P, FZD4, MRGPRX3, MRGPRX4, GPBAR1, CYSLTR2, LPAR3 | Background: Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei and is an endogenous ligand for APJ, a G protein-coupled orphan receptor which is an alternative coreceptor with CD4 for HIV-1. Apelin and APJ are ubiquitously expressed in peripheral tissues, with highest levels reported for heart and lungs, as well several regions within the central nervous system. The actions of apelin remain largely unknown: Apelin inhibits HIV-1 entry in cells coexpressing CD4 and APJ; the oral intake of Apelin in colostrum and breast milk could have a role in the modulation of the immune responses in neonates; more recent studies have also indicated a role for Apelin in the central control of body fluid homeostasis, by influencing AVP release and drinking behavior. In the cardiovascular system several actions of Apelin have been described, including endothelium-dependent vasodilatation, vasoconstriction through direct action on smooth muscle and positive inotropism. Species: | Reactivity: | Human, Mouse, Rat and Bovine. | Applications: | Uses: | Immunohistochemistry and Western Blot | | Dilutions: | immunohistochemistry 1:100 to 1:500, Western Blot 1:500 to 1:2000 | Notes: Reconstitute in 200 ul of distilled water. Packaging: | Buffer: | Lyophilized 0.02 ml Whole Rabbit antisera. | | Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. | | Preservative: | No Preservative | | Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. | |
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