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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-24-368468 |
AP11745PU-N |
ACO2//Human, Mouse, Rat/Rabbit |
1/EA |
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¹®ÀÇ |
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Subject
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ACO2 |
Description
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/ Human, Mouse, Rat/Rabbit |
Clonality
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Mono |
Company
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Acris Antibodies GmbH |
Application
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Enzyme Immunoassay, Western blot / Immunoblot |
Conjugation
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Immunogen
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Contents
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Description: Manufacturer | Acris Antibodies GmbH | Quantity | 0.1 mg | Reactivity | Human, Mouse, Rat | Presentation | Purified | Applications | Enzyme Immunoassay, Western blot / Immunoblot | Isotype | Ig | Host | Rabbit | PDF datasheet | view | Shipping to | Worldwide | Synonyms | Aconitase 2 | Swiss Prot Num | Q99798 | Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human Aconitase. | Product Type | Antibodies | Storage | Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | References | 1. Juang, H.H., Mol. Genet. Metab. 81(3):244-252 (2004). 2. Bota, D.A., et al., Nat. Cell Biol. 4(9):674-680 (2002). 3. Gruer, M.J., et al., Trends Biochem. Sci. 22(1):3-6 (1997). 4. Klausner, R.D., et al., Mol. Biol. Cell 4(1):1-5 (1993). 5. Geurts van Kessel, A.H., et al., Cytogenet. Cell Genet. 28(3):169-172 (1980). | |
Format | State: Liquid Ig fraction | ? | Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS | ? | Buffer System: PBS with 0.09% (W/V) sodium azide | |
Specificity | This antibody detects ACO2 at center. | Add. information | Molecular weight: 85425 Da. | Application | ELISA 1:1,000. Western blot 1:100 - 1:500. | Background | ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. | Concentration | 0.25 mg/ml | |
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