|
|
Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-24-368521 |
AP01172PU-N |
ACVRL1 / ALK1//Human, Mouse, Rat/Rabbit |
1/EA |
|
|
|
|
¹®ÀÇ |
|
|
|
|
|
|
Subject
|
ACVRL1 / ALK1 |
Description
|
/ Human, Mouse, Rat/Rabbit |
Clonality
|
Mono |
Company
|
Acris Antibodies GmbH |
Application
|
Enzyme Immunoassay, Immunofluorescence, Paraffin Sections, Western blot / Immunoblot |
Conjugation
|
|
Immunogen
|
|
Contents
|
Description: Manufacturer | Acris Antibodies GmbH | Quantity | 100 ug | Reactivity | Human, Mouse, Rat | Presentation | Aff - Purified | Applications | Enzyme Immunoassay, Immunofluorescence, Paraffin Sections, Western blot / Immunoblot | Host | Rabbit | PDF datasheet | view | Shipping to | Worldwide | Synonyms | ACVRLK1, Activin receptor-like kinase 1, SKR3 | Swiss Prot Num | P37023 | Product Type | Antibodies | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch | |
Format | State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE). | ? | Purification: Affinity Chromatography using epitope-specific immunogen. | ? | Buffer System: Phosphate buffered saline (PBS), pH~7.2 containing 15 mM Sodium Azide as preservative. | |
Specificity | This antibody detects endogenous levels of ALK-1 protein. | Application | Western Blot: 1/500-1/1000. ELISA: 1/20000-1/40000. Immunohistochemistry: 1/50-1/200. Immunofluorescence: 1/50-1/200. | Background | LTK, ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the insulin receptor subfamily of kinases. LTK (leukocyte tyrosine kinase) is expressed in murine B lymphocyte precursors and has also been found in forebrain neurons. ALK (anaplastic lymphoma kinase) is normally highly expressed, specifically in the nervous system. A truncated form containing the catalytic domian of ALK is expressed as the result of a translocation occuring in many non-Hodgkinu¢âs lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development. | Concentration | 1.0 mg/ml | |
|
|
|
|