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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-368522 |
AP14608PU-N |
ACVRL1 / ALK1//Human, Mouse/Rabbit |
1/EA |
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문의 |
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Subject
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ACVRL1 / ALK1 |
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Description
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/ Human, Mouse/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 0.1 mg | | Reactivity | Human, Mouse | | Presentation | Purified | | Applications | Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot | | Isotype | Ig | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | ACVRLK1, Activin receptor-like kinase 1, SKR3 | | Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Human ACVRL1. | | Product Type | Antibodies | | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | | References | 1. Yu, Ming-Jiun, et al. Mol. Cell. Proteomics 2006 Nov 01;5(11):2131-2145. (Applications: IF) 2. Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). 3. Berg, J.N., et al., Am. J. Hum. Genet. 61(1):60-67 (1997). 4. Johnson, D.W., et al., Nat. Genet. 13(2):189-195 (1996). 5. ten Dijke, P., et al., Oncogene 8(10):2879-2887 (1993). 6. Attisano, L., et al., Cell 75(4):671-680 (1993). | |
| Format | State: Liquid purified Ig fraction. | | ? | Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. | | ? | Buffer System: PBS with 0.09% (W/V) Sodium Azide as preservative. | |
| Specificity | This antibody recognizes ACVRL1. | | Add. information | Calculated Molecular Weight: 56124 Da | | Application | ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50- 1/100. Immunofluorescence. (See Ref.1) | | Background | ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. | | Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. | | Concentration | 0.25 mg/ml | | Species Reactivity | Tested: Human and Mouse. | |
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