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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-368537 |
AP14085PU-N |
ADAMTS13//Human/Rabbit |
1/EA |
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문의 |
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Subject
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ADAMTS13 |
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Description
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/ Human/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Enzyme Immunoassay, Western blot / Immunoblot |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 0.1 mg | | Reactivity | Human | | Presentation | Aff - Purified | | Applications | Enzyme Immunoassay, Western blot / Immunoblot | | Isotype | Ig | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | ADAMTS-13, ADAM-TS13, C9orf8, vWF-cleaving protease | | Swiss Prot Num | Q76LX8 | | Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ADAMTS13. | | Product Type | Antibodies | | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | | References | 1. Zheng X., Chung D., Takayama T.K.J. Biol. Chem. 276:41059-41063(2001) 2. Levy G.G., Nichols W.C.Nature 413:488-494(2001) 3. Cal S., Obaya A.J., Llamazares M., Garabaya C.Gene 283:49-62(2002) 4. Zheng X., Nishio K., Majerus E.M.J. Biol. Chem. 278:30136-30141(2003) 5. Anderson P.J., Kokame K., Sadler J.E.J. Biol. Chem. 281:850-857(2006) 6. Pimanda J.E., Maekawa A., Wind T.Blood 103:627-629(2004) 7. Plaimauer B., Fuhrmann J., Mohr G.Blood 107:118-125(2006) | |
| Format | State: Liquid purified Ig | | ? | Purification: Protein A column, followed by peptide affinity purification | | ? | Buffer System: PBS with 0.09% (W/V) sodium azide | |
| Specificity | This antibody reacts to ADAMTS13. | | Application | ELISA: 1/1,000. Western blotting: 1/50 - 1/100. | | Background | ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. | | Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. | | Concentration | 0.25 mg/ml | |
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