Synonyms | ADAMTS-4, ADAM-TS4, Aggrecanase-1, ADMP1, ADMP-1, KIAA0688 |
Swiss Prot Num | O75173 |
Immunogen | Synthetic peptide corresponding to the C-terminal region of human ADAMTS-4 |
Product Type | Antibodies |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
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Format | State: Liquid purified Ig |
? | Purification: Affinity chromatography |
? | Buffer System: PBS containing 0.05% Sodium Azide and 50% Gycerol |
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Specificity | This antibody is specific for ADAMTS-4 (A Disintegrin And Metalloproteinase with Thrombospondin motif -4), also known as Aggrecanase-1. |
Application | Immunohistochemistry on frozen sections. Western Blot: 1:1000. |
Background | ADAMTS-4 is secreted into the extracellular matrix and is known to cleave aggreca, n versican and brevican. ADAMTS-4 has been implicated in arthritis. |
Caution | (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. |
Concentration | 1.0 mg/ml |