| Synonyms | ADAMTS-5, ADAM-TS5, ADAMTS11, ADMP2, Aggrecanase-2, ADMP-2, |
| Swiss Prot Num | Q9UNA0 |
| Immunogen | Synthetic peptide corresponding to the C-terminal region of human ADAMTS-5 |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
|
| Format | State: Liquid purified Ig |
| ? | Purification: Affinity chromatography |
| ? | Buffer System: PBS containing 0.05% Sodium Azide and 50% Gycerol |
|
| Specificity | This antibody is specific for ADAMTS-5 (A Disintegrin And Metalloproteinase with Thrombospondin motif-5), also known as Aggrecanase-2. |
| Application | Immunohistochemistry on frozen sections. Western Blot: 1:1000. |
| Background | ADAMTS-5 is secreted into the extracellular cell matrix by several cell types including synovial and fibroblast cells. ADAMTS-5 has been shown to cleave aggrecan and has been implicated in cartilage destruction, such as that seen in arthritis. |
| Caution | (A full Health and Safety assessment is available upon request) This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. |
| Concentration | 1.0 mg/ml |
