Synonyms | TRAF3IP2, C6orf4, C6orf5, C6orf6, ACT1 |
Swiss Prot Num | O43734 |
Immunogen | Synthetic peptide corresponding to amino acids 554-568 of human CIKS. |
Product Type | Antibodies |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
References | 1. Leonard, A. et al. (2000) CIKS, a connection to I Kappa B Kinase and stress-activated protein kinase. Proc. Natl. Acad. Sci. 12: 10494 - 9. |
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Format | State: Liquid purified IgG |
? | Purification: Affinity chromatography |
? | Buffer System: BPS containing 0.02% Sodium Azide |
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Specificity | This antibody recognises an epitope within the c-terminal region of the CIKS molecule (for connection to IKK and SAPK/JNK), also known as Act 1. |
Application | Western Blot: 1 ?g/ml; A band of approximately 63kD is detected. |
Background | CIKS has been shown to interact directly with the regulatory subunit of I Kappa Kinase (IKK), resulting in the activation of NF kB. CIKS/Act 1 is ubiquitously expressed in human tissues. |
Concentration | 0.5 mg/ml |