Synonyms | ADCY2, KIAA1060, Adenylate cyclase type II, ATP pyrophosphate-lyase 2, Adenylyl cyclase 2 |
Swiss Prot Num | Q08462 |
Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ADCY2. |
Product Type | Antibodies |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
References | 1. Uhl,G.R.,Arch. Gen. Psychiatry 65 (6), 683-693 (2008) 2. Ludwig,M.G.,J. Recept. Signal Transduct. Res. 22 (1-4), 79-110 (2002) 3. Cote,M., J. Clin. Endocrinol. Metab. 86 (9), 4495-4503 (2001) |
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Format | State: Liquid purified Ig fraction. |
? | Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
? | Buffer System: PBS with 0.09% (W/V) Sodium Azide as preservative. |
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Specificity | This antibody detects Adenylate Cyclase 2 (ADCY2) (C-term). |
Add. information | Molecular weight: 123603 Da |
Application | ELISA: 1/1,000. Western Blot: 1/50-1/100. Immunohistochemistry: 1/10-1/50. |
Background | ADCY2 is a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate(cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex. |
Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Concentration | 0.25 mg/ml |