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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-24-368585 |
AP15163PU-N |
Adenylate kinase 1 (AK1)//Human, Hamster/Rabbit |
1/EA |
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Subject
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Adenylate kinase 1 (AK1) |
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Description
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/ Human, Hamster/Rabbit |
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Clonality
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Mono |
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Company
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Acris Antibodies GmbH |
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Application
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Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot |
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Conjugation
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Immunogen
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Contents
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Description: | Manufacturer | Acris Antibodies GmbH | | Quantity | 0.1 mg | | Reactivity | Human, Hamster | | Presentation | Purified | | Applications | Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot | | Isotype | Ig | | Host | Rabbit | | PDF datasheet | view | | Shipping to | Worldwide | | Synonyms | Myokinase | | Swiss Prot Num | P00568 | | Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human AK1. | | Product Type | Antibodies | | Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. | | References | 1. Corrons, J.L., et al., Blood 102(1):353-356 (2003). 2. Toren, A., et al., Br. J. Haematol. 87(2):376-380 (1994). 3. Zuffardi, O., et al., Hum. Genet. 82(1):17-19 (1989). 4. Matsuura, S., et al., J. Biol. Chem. 264(17):10148-10155 (1989). 5. Miwa, S., et al., Am. J. Hematol. 14(4):325-333 (1983). | |
| Format | State: Liquid purified Ig | | ? | Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS | | ? | Buffer System: PBS with 0.09% (W/V) sodium azide | |
| Specificity | This antibody reacts to AK1. | | Application | ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100. | | Background | Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. | | Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. | | Concentration | 0.25 mg/ml | |
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