| Synonyms | AK3L1, AK3, Adenylate kinase 3-like |
| Swiss Prot Num | P27144 |
| Immunogen | This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human AK3. |
| Product Type | Antibodies |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Biochem. J. 358 (PT 1), 225-232 (2001) 2. Eur. J. Biochem. 261(2):509-517 (1999). 3. Brain Res. Mol. Brain Res. 62(2):187-195 (1998). 4. Genomics 13(3):537-542 (1992). 5. Cytogenet. Cell Genet. 32 (1-4), 144-152 (1982). |
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| Format | State: Liquid purified Ig |
| ? | Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS |
| ? | Buffer System: PBS with 0.09% (W/V) sodium azide |
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| Specificity | This antibody reacts to AK3. |
| Application | ELISA: 1/1,000. |
| Background | AK3 is a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for the AK3 gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene, which sequence alignment suggests is located on chromosome 1. |
| Caution | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Concentration | 0.25 mg/ml |
