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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-44-10268 |
51-0700 |
Anti-14-3-3 Polyclonal Antibody, Unconjugated, Clone BN20/200 ¥ìg/Human, mouse, rat, bovine, C.elegans, Xenopus/Request Info |
1/EA |
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¹®ÀÇ |
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Subject
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Anti-14-3-3 Polyclonal Antibody, Unconjugated, Clone BN20 |
Description
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200 ¥ìg / Human, mouse, rat, bovine, C.elegans, Xenopus/Request Info |
Clonality
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Poly |
Company
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Invitrogen |
Application
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ELISA, Western blotting |
Conjugation
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Unconjugated |
Immunogen
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14-3-3 |
Contents
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14-3-3 proteins are a family of small, widely expressed, highly conserved cytosolic proteins. 14-3-3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction, cell cycle regulation and apoptosis including Raf, PKC, Bad, Cbl, and c-Bcr. Interactions between 14-3-3 and target proteins are strongly influenced by the phosphorylation state of 14-3-3 and the target protein. 14-3-3 expression is particularly high in certain neural tissues and studies in Drosophila have established a role for 14-3-3 proteins in nervous system development and function. Recently, a dimeric 14-3-3 protein was determined to be an essential cofactor for Raf kinase activity. |
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