Catalog Number | GTX104491 |
Product Name | Kallikrein-6 antibody |
Full Name | kallikrein-related peptidase 6 |
Product Description | Rabbit polyclonal antibody to Kallikrein-6 (kallikrein-related peptidase 6) |
Synonyms | Bssp | Klk7 | MGC9355 | NEUROSIN | PRSS18 | PRSS9 | SP59 | ZYME | hK6 |
Background | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimers disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq] |
Clonality | Polyclonal |
Host | Rabbit |
Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 213 of Human Kallikrein-6 |
Antigen Species | Human |
Tested Applications | Dot Blot |
Application Note | Further validation in progress. |
Specificity | This antibody is specific to the Protein antigen from Kallikrein-6. |
Species Cross Reactivity | Human - Not yet tested in other species |
Positive Controls | Target recombinant protein |
Target | Kallikrein-6 |
Predicted Target Size(KDa) | 26.86 |
Cellular Localization | Secreted | Nucleus | nucleolus | Cytoplasm | Mitochondrion | Microsome |
Form Supplied | Liquid |
Concentration | 0.88 mg/ml |
Purification | Purified by antigen-affinity chromatography. |
Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage Instruction | Keep as concentrated solution. Aliquot and store at -20¨¬C or below. Avoid multiple freeze-thaw cycles. |
Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |