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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-25-386117 |
GTX71885 |
ADAMTS5//Human/Rabbit |
1/EA |
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¹®ÀÇ |
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Subject
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ADAMTS5 |
Description
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/ Human/Rabbit |
Clonality
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Mono |
Company
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GeneTex |
Application
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Paraffin Sections |
Conjugation
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Immunogen
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Contents
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Description: Manufacturer | GeneTex Inc. | Quantity | 25 ug | Reactivity | Human | Applications | Paraffin Sections | Isotype | IgG | Host | Rabbit | PDF datasheet | view | Shipping to | Europe only | Synonyms | ADAMTS-5, ADAM-TS5, ADAMTS11, ADMP2, Aggrecanase-2, ADMP-2, | Swiss Prot Num | Q9UNA0 | Immunogen | Synthetic peptide - KLH conjugated | Product Type | Antibodies | Storage | Keep as concentrated solution. Store at 4 | |
Format | State: Liquid | ? | Purity: Immunogen affinity purified. | ? | Purification: Immunogen affinity purified. | ? | Buffer System: Phosphate buffered saline, PH 7.7 containing 0.01% sodium azide | |
Specificity | Human. Others not determined. | Application | IHC-P | Background | ADAMTS5, also known as aggrecanase-2, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan. The protein contains a signal sequence, a prodomain with both a potential cysteine switch and a furin cleavage site, a metalloproteinase domain with a conserved zinc-binding motif and a 'met turn,' a disintegrin-like domain, and a spacer region between a thrombospondin type 1 motif and thrombospondin submotif. At least four transcript variants have been reported. ADAMTS5 has been implicated in inflammatory joint diseases. ADAMTS5 expression has been documented in a range of normal human tissues. ESTs have been isolated from human tissue libraries, including normal breast, embryo and heart and cancerous placenta and uterus. | Concentration | 1 mg/ml | |
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