| Catalog Number | GTX13702 |
| Product Name | ADAMTSL1 [30D445.1] antibody |
| Product Description | Mouse monoclonal [30D445.1] to ADAMTSL1 |
| Synonyms | 92949 | ADAMTSL1 | 609198 | Q8N6G6 | ADAMTSR1 | MGC40193 | |
| Background | ADAMTSL1 is a secreted molecule, expressed in adult skeletal muscle, resembling members of the ADAMTS family of proteases, containing four thrombospondin type I repeats. Human ADAMTSL1 cleaves aggrecan and is thereby classified as an aggrecanase. Like the ADAMTS proteases, each domain in ADAMTSL1 has an even number of cysteine residues suggesting that each domain may have internal disulfide bonds and that punctin consists of a series of independently folded and disulfide-bonded domains. |
| Clonality | Monoclonal |
| Clone No | 30D445.1 |
| Host | Mouse |
| Isotype | IgM |
| Immunogen | Synthetic peptide (Human). |
| Antigen Species | Human |
| Tested Applications | Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | WB: Use at a dilution of 1/250 - 1/500. Detects a band of approximately 60 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | Human muscle cell lysate. |
| Target | ADAMTSL1 |
| Cellular Localization | Secreted. Associated with the extracellular matrix. |
| Purification | Purified IgM |
| Storage Buffer | Preservative: 0.02% Sodium Azide; Constituents: PBS |
| Storage Instruction | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
Image:img24284.jpgWestern Blot analysis of ADAMTSL1 using GTX13702 at a 1:250 dilution against human heart. Print:Print
