| Catalog Number | GTX23648 |
| Product Name | Adenovirus [M58 + M73] antibody |
| Product Description | Mouse monoclonal [M58 + M73] to Adenovirus |
| Synonyms | EIA |
| Background | The adenovirus early gene products E1A is a potent stimulator of cellular proliferation, which when overexpressed can overcome the growth inhibitory effects of TGF beta. The E1A region encodes a series of related proteins (35 - 46 kD) with multifunctional capabilities and forms a specific complex with the retinoblastoma tumor suppressor gene product. The E1a and E1B regions together comprise the transforming region of adenovirus. While expression of E1A alone is sufficient to immortalize primary cells, complete transformation requires the additional expression of the E1B region. |
| Clonality | Monoclonal |
| Clone No | M58 + M73 |
| Host | Mouse |
| Isotype | IgG2a |
| Immunogen | Adenovirus. |
| Tested Applications | IHC (Frozen sections), IHC (Formalin-fixed paraffin-embedded sections). The usefulness of this product in other applications has not been determined. |
| Application Note | Immunohistochemistry (formalin fixed paraffin embedded / frozen sections): use at a dliution of 1/50 - 1/75 in an ABC method. Not tested in other applications. Optimal dilutions / concentrations should be determined by the end user. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. |
| Positive Controls | Suitable tissue control sections for Immunohistochemistry: Adenovirus infected tissue. |
| Target | Adenovirus |
| Cellular Localization | Nuclear. |
| Form Supplied | Liquid |
| Purification | IgG fraction |
| Storage Buffer | Liquid with sodium azide |
| Storage Instruction | Keep as concentrated solution, aliquot and store at 4°C. |
Image:img4239.jpgIHC image using GTX23648 - Detection of adenovirus by IHC in human infected appendix Print:Print
