| Catalog Number | GTX27397 |
| Product Name | ACHE antibody (HRP) |
| Product Description | Goat polyclonal to Acetylcholinesterase ( HRP ) |
| Synonyms | 540446 | ACHE | |
| Background | Cholinergic neurotransmission occurs in motor, autonomic and central nervous synapses and requires very rapid inactivation of its transmitter, acetylcholine (ACh). Acetylcholinesterase (AChE) rapidly hydrolyzes ACh to acetate and choline, thereby inactivating it. AChE is found in the neuromuscular junction anchored to the basal lamina which runs between the nerve terminal and muscle membrane. AChE is also found outside the nervous and neuromuscular system in blood, lymph, germ and liver cells suggesting a role for AChE not related to cholinergic transmission. Another less specific cholinesterase, butyrylcholinesterase (BChE), seems to contribute to the regulation of the ACh concentration in the synaptic cleft. |
| Clonality | Polyclonal |
| Host | Goat |
| Isotype | IgG |
| Immunogen | Acetyl Cholinesterase [Bovine Erythrocytes] |
| Antigen Species | Bovine |
| Tested Applications | ELISA, IHC (Frozen sections), Immunomicroscopy, Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | Suitable for immunoblotting (western or dot blot), ELISA (1:1000), immunoperoxidase electron microscopy and immunohistochemistry as well as other peroxidase-antibody based enzymatic assays. |
| Species Cross Reactivity | Cross-reacts with Cow. Not yet tested in other species. |
| Target | ACHE |
| Conjugation | HRP |
| Conjuation Note | Horseradish Peroxidase (HRP). |
| Form Supplied | Liquid |
| Purification | IgG fraction |
| Purification Note | This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer |
| Storage Buffer | Stabilizer: 10 mg/ml Bovine Serum Albumin (BSA) IgG and Protease free Preservative: 0.01% (w/v) Gentamicin Sulfate Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
| Storage Instruction | Store at +4°C short term. Aliquot and store at -20°C or -80°C |
