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Cat. No |
Model |
Description |
Unit |
Price (VATº°µµ) |
³³±â |
Àç°í |
DataSheet |
ÁÖ¹®/°ßÀû |
LCA-25-386097 |
GTX15138 |
Acrolein antibody//Human,Rabbit/Rabbit |
1/EA |
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Subject
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Acrolein antibody |
Description
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/ Human,Rabbit/Rabbit |
Clonality
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Poly |
Company
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GeneTex |
Application
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ELISA |
Conjugation
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Immunogen
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Contents
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Catalog Number | GTX15138 | Product Name | Acrolein antibody | Product Description | Rabbit polyclonal to Acrolein | Background | Acrolein, a reactive alpha,beta-unsaturated aldehyde, is a common environmental pollutant, a metabolite of the anticancer drug cyclophosphamide, and a byproduct of lipid peroxidation. An increase in acrolein production has been proposed as a marker for Alzheimers disease, diabetic glomerular lesions, and atherosclerosis. Acrolein is a potent inhibitor of cell proliferation at nonlethal doses and may act through effects on redox-regulated transcription factors. It has been reported that NF-kappaB activation is inhibited by acrolein. | Clonality | Polyclonal | Host | Rabbit | Isotype | IgG | Immunogen | Acrolein carriers. | Tested Applications | ELISA. The usefulness of this product in other applications has not been determined. | Application Note | ELISA: Use at a dilution of 1/2000 - 1/5000. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. | Specificity | Using a conjugate Acrolein Protein, antibody specificity was performed with an ELISA test by competition experiments with the following compounds.Acrolein-BSA (ratio 1:1), Malondialdehyde-BSA (1:55), Glyoxal-BSA (1:> 50,000), Formaldehyde-BSA (1:> 50,000), Glutaraldehyde-BSA (1/> 50,000). Crossreactivity ratio is the Acrolein BSA concentration/unconjugated or conjugated analogs concentration at half displacement. | Target | Acrolein | Purification | Immunogen affinity purified | Storage Buffer | Preservative: NoneConstituents: 40% Glycerol, PBS | Notes | For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer." | |
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