| Catalog Number | GTX27428 |
| Product Name | Adenovirus [B025 / AD51] antibody |
| Product Description | Mouse monoclonal [B025/AD51] to Adenovirus |
| Background | Adenoviruses are DNA viruses generally widespread in nature that are frequently the cause of acute upper respiratory tract infections (i.e. common colds). Forty-seven known serotypes have been isolated since they were first discovered in 1953 with 3 types known to cause gastroenteritis. Several types have oncogenic potential though most cause self-limiting febrile illnesses characterized by inflammation of conjunctivae and the respiratory tract. The virus can be isolated from the majority of tonsils/adenoids surgically removed, indicating latent infections. It is not known how long the virus can persist in the body, or whether it is capable of reactivation after long periods. In patients experiencing immunosuppression (e.g. AIDS) it can be reactivated causing disease. |
| Clonality | Monoclonal |
| Clone No | B025 / AD51 |
| Host | Mouse |
| Isotype | IgG2a |
| Immunogen | Adenovirus type 3 (ATCC strain VR847) |
| Tested Applications | ELISA, IHC (Frozen sections), IHC (Formalin-fixed paraffin-embedded sections). The usefulness of this product in other applications has not been determined. |
| Application Note | For ELISA, IHC-Fr and IHC-P: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. |
| Specificity | GTX27248 recognises all Adenovirus serotypes by binding to the hexon polypeptide. |
| Species Cross Reactivity | No cross-reactions are known |
| Target | Adenovirus |
| Form Supplied | Liquid |
| Purification | Protein A affinity purified |
| Purification Note | From hybridoma culture supernatant |
| Storage Buffer | PBS, pH7.2 with 0.09% sodium azide as preservative. |
| Storage Instruction | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Notes | With recent studies indicating that viral agents may be implicated in new emerging diseases reported around the world, interest in viruses has increased and encompassed many different viral genera. The adenoviruses are represented by several different groups yet there are only few monoclonal antibodies that are commercially available that recognise all known serotypes." |
