Catalog Number | GTX20919 |
Product Name | ACTH antibody (ready-to-use) |
Product Description | Rabbit polyclonal to ACTH prediluted |
Synonyms | 5443 | POMC | 176830 | P01189 | ACTH | CLIP | LPH | MSH | NPP | POC | |
Background | ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. |
Clonality | Polyclonal |
Host | Rabbit |
Isotype | IgG |
Immunogen | Synthetic peptide, corresponding to amino acids 1-24 of Human ACTH. |
Antigen Species | Human |
Tested Applications | IHC (Frozen sections), IHC (Formalin-fixed paraffin-embedded sections). The usefulness of this product in other applications has not been determined. |
Application Note | This antibody has been pretitered and quality controlled to work allon formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections. No further titration is required. We suggest an incubation period of 30-60 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user. |
Specificity | This antibody reacts with human ACTH. It cross reacts with ACTH in a wide variety of mammalian species. Traces of contaminating antibodies have been removed by solid phase absorption. |
Species Cross Reactivity | Human - Not yet tested in other species |
Target | ACTH |
Cellular Localization | Secreted |
Form Supplied | Liquid |
Purification | Protein A purified |
Storage Buffer | PBS with sodium azide |
Storage Instruction | Keep as concentrated solution, aliquot and store at 4¡ÆC. Do not freeze. |