| Catalog Number | GTX74295 |
| Product Name | ACTH antibody (ready-to-use) |
| Product Description | Rabbit polyclonal to ACTH |
| Synonyms | 5443 | POMC | 176830 | P01189 | ACTH | CLIP | LPH | MSH | NPP | POC | |
| Background | ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Synthetic human ACTH conjugated to KLH |
| Antigen Species | Human |
| Tested Applications | IHC (Frozen sections), IHC (Formalin-fixed paraffin-embedded sections). The usefulness of this product in other applications has not been determined. |
| Application Note | For IHC-Fr: Use at a Neat dilution. For IHC-P: Use at a Neat dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. |
| Specificity | Recognizes human adenocorticotrophin (ACTH), a 39 amino acid cleavage product from pro-opiomelanocortin (POMC) which elicits a classic glucocorticoid response from the adrenal glands in situations of stress. ACTH is produced in the pituitary, and also by lymphocytes and macrophages. |
| Species Cross Reactivity | Human and rabbit - Not yet tested in other species |
| Positive Controls | Pituitary gland |
| Target | ACTH |
| Form Supplied | Liquid, ready to use |
| Purification | Unpurified |
| Purification Note | From polyclonal serum |
| Storage Buffer | Phosphate buffered saline containing 0.09% sodium azide and 1% BSA |
| Storage Instruction | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Notes | No current publications for this product |
