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Description |
Unit |
Price
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납기 |
재고 |
DataSheet |
주문/견적 |
| LCA-25-386250 |
GTX74132 |
A2M antibody//Cow,horse,guineapig,pig,dog,cat,Human,,rabbit/Sheep |
1/EA |
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문의 |
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Subject
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A2M antibody |
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Description
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/ Cow,horse,guineapig,pig,dog,cat,Human,,rabbit/Sheep |
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Clonality
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Poly |
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Company
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GeneTex |
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Application
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DID, Ie, IRMA, RID |
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Conjugation
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Immunogen
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Contents
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| Catalog Number | GTX74132 | | Product Name | A2M antibody | | Product Description | Sheep polyclonal to Alpha-2 Macroglobulin | | Synonyms | A2M antibody Alpha 2 M antibody Alpha 2M antibody Anti-A2M Anti-Alpha 2 M Anti-Alpha 2M Anti-CPAMD5 Anti-DKFZp779B086 Anti-FWP007 Anti-S863 7 Anti-alpha 2 Macroglobulin CPAMD5 antibody DKFZp779B086 antibody FWP007 antibody S863 7 antibody | | Background | Alpha 2 macroglobulin is a serum protein which is mainly synthesised in the liver. It functions as a broad range irreversible proteinase inhibitor that forms a "trap" around most proteases. Alpha 2 macroglobulin is a tetrameric molecule, and with a molecular weight of 720 kDa, it so large a molecule that it tends to remain intravascular. Following conformational change the proteinase is deposited within a central cavity where it is still active but prevented from further contact with its substrate. Removal of the complex is mediated by the generation of recognition sites which react with receptors on a variety of cells including macrophages and liver cells. Alpha 2 macroglobulin is localized on the surface of peripheral blood lymphocytes. | | Clonality | Polyclonal | | Host | Sheep | | Immunogen | Human alpha 2 -macroglobulin purified from plasma | | Antigen Species | Human | | Tested Applications | Double immunodiffusion, Immunoelectrophoresis, Immunoradiometric assay, Radial immunodiffusion. The usefulness of this product in other applications has not been determined. | | Application Note | For ID: Use at an assay dependent dilution. For IHC-Fr: Use at an assay dependent dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher. | | Specificity | Recognizes alpha 2-macroglobulin, a tetrameric glycoprotein of 720kD which functions as a proteinase inhibitor. | | Species Cross Reactivity | Cow, horse, guinea pig, pig, dog, cat, human, and rabbit - Not yet tested in other species | | Target | A2M | | Form Supplied | Liquid | | Purification | Purified IgG | | Purification Note | From polyclonal serum - ion exchange - 18.6mg/ml | | Storage Buffer | Glycine buffered saline pH7.4 containing 0.09% Sodium Azide, 0.1% EACA, 0.01% Benzamidine, 1mM EDTA | | Storage Instruction | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. | |
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