| Catalog Number | GTX15198 |
| Product Name | D4 GDI antibody |
| Product Description | Rabbit polyclonal to D4 GDI |
| Synonyms | 397 | ARHGDIB | 602843 | P52566 | D4 | GDIA2 | GDID4 | LYGDI | Ly-GDI | RAP1GN1 | |
| Background | D4 GDI belongs to the family of Rho GDIs or GDP dissociation inhibitors for the Rho/Rac family of small G proteins; consisting of RhoGDI 1, D4 GDI/RhoGDI2 and Rho GDI3. It inhibits the release of GDP from the Rho proteins, essential for GTP loading and activation of GTPase activity. D4 GDI is located in the cytoplasm and in involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas mediated apoptosis. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Isotype | IgG |
| Immunogen | Recombinant full length protein (Human). |
| Antigen Species | Human |
| Tested Applications | IHC (Formalin-fixed paraffin-embedded sections), Western blot. The usefulness of this product in other applications has not been determined. |
| Application Note | IHC-P: Use at a dilution of 1/100 for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. WB: Use at a concentration of 1 μg/ml for 2hours. Predicted molecular weight: 23 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | Placenta and tonsil |
| Target | D4 GDI |
| Cellular Localization | Cytoplasmic and Nuclear |
| Form Supplied | Liquid |
| Purification | Immunogen affinity purified |
| Storage Buffer | Phosphate-buffered saline, pH 7.4 containing 1% BSA and 0.09% sodium azide |
| Storage Instruction | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
Image:img25357.jpgGTX15198 staining D4 GDI in human tonsil by Immunohistochemistry (FFPE-sections). Print:Print
