| Catalog Number | GTX101730 |
| Product Name | Rab GDI alpha antibody |
| Full Name | GDP dissociation inhibitor 1 |
| Product Description | Rabbit polyclonal antibody to Rab GDI alpha (GDP dissociation inhibitor 1) |
| Synonyms | FLJ41411 | GDIL | MRX41 | MRX48 | OPHN2 | RABGD1A | RABGDIA | XAP-4 |
| Background | GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 198 of Human Rab GDI alpha |
| Antigen Species | Human |
| Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Specificity | This antibody is specific to the Human Rab GDI alpha protein. |
| Species Cross Reactivity | Tested with Human antigen. Other species have not been tested. |
| Positive Controls | 293T |
| Target | Rab GDI alpha |
| Predicted Target Size(KDa) | 50.59 |
| Cellular Localization | Cytoplasm |
| Form Supplied | Liquid |
| Concentration | 0.27 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX101730 WB ImageWestern Blot analysis of GDI1 expression in transfected 293T cell line by GDI1 polyclonal antibody. A: Non-transfected lysate. B: GDI1 transfected lysate. 12% SDS PAGEGTX101730 diluted at 1:500Print:Print
