| Catalog Number | GTX111895 |
| Product Name | Macrophage erythroblast attacher antibody |
| Full Name | macrophage erythroblast attacher |
| Product Description | Rabbit polyclonal antibody to Macrophage erythroblast attacher (macrophage erythroblast attacher) |
| Synonyms | EMLP | EMP | HLC-10 | PIG5 |
| Background | This gene product mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. This protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Two immunologically related isoforms of erythroblast macrophage protein with apparent molecular weights of 33 kD and 36 kD were detected in macrophage membranes; this gene encodes the larger isoform. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 257 and 319 of Macrophage erythroblast attacher |
| Antigen Species | Human |
| Tested Applications | Dot blot |
| Application Note | Further validation in progress. |
| Specificity | This antibody is specific to the Peptide antigen from Macrophage erythroblast attacher. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | Synthetic peptide: 1:8,000 |
| Target | Macrophage erythroblast attacher |
| Predicted Target Size(KDa) | 40.42 |
| Cellular Localization | Nucleus matrix | Cell membrane | Cytoplasm | cytoskeleton |
| Form Supplied | Liquid |
| Concentration | 1 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
