| Catalog Number | GTX108338 |
| Product Name | NAK antibody |
| Full Name | TANK-binding kinase 1 |
| Product Description | Rabbit polyclonal antibody to NAK (TANK-binding kinase 1) |
| Synonyms | FLJ11330 | NAK | T2K |
| Background | The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. For example, the protein can form a complex with the IKB protein TANK and TRAF2 and release the NFKB inhibition caused by TANK. [provided by RefSeq] |
| Clonality | Polyclonal |
| Host | Rabbit |
| Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 666 and 729 of NAK |
| Antigen Species | Human |
| Tested Applications | WB and IF. The usefulness of this product in other applications has not been determined. |
| Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000，IF:1:100-1:200. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
| Specificity | This antibody is specific to the Human NAK protein. |
| Species Cross Reactivity | Human - Not yet tested in other species |
| Positive Controls | 293T | A431 | H1299 | HeLaS3 | HepG2 | Molt-4 | Raji |
| Target | NAK |
| Predicted Target Size(KDa) | 83.65 |
| Cellular Localization | Cytoplasm |
| Form Supplied | Liquid |
| Concentration | 0.39 mg/ml |
| Purification | Purified by antigen-affinity chromatography. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Storage Instruction | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX108338 WB ImageSample(30μg of whole cell lysate)A: 293TB: A431 (GTX27909)C: H1299D: HeLa S3 (GTX14654)E: Hep G2 (GTX27900)F: MOLT4 (GTX27912)G: Raji (GTX27908)7.5% SDS PAGEGTX108338 diluted at 1:5000GTX108338 IF ImageImmunofluorescence analysis of HeLa, using NAK(GTX108338) antibody at 1:100 dilution.Print:Print
