Catalog Number | GTX110516 |
Product Name | TACC2 antibody |
Full Name | transforming, acidic coiled-coil containing protein 2 |
Product Description | Rabbit polyclonal antibody to TACC2 (transforming, acidic coiled-coil containing protein 2) |
Synonyms | AZU-1 | ECTACC |
Background | Transforming acidic coiled-coil proteins are a conserved family of centrosome- and microtubule-interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is induced by erythropoietin and is thought to affect the progression of breast tumors. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Clonality | Polyclonal |
Host | Rabbit |
Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 237 and 303 of TACC2 |
Antigen Species | human |
Tested Applications | WB and IHC-P. The usefulness of this product in other applications has not been determined. |
Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000,IHC-P: 1:100-1:500. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
Specificity | This antibody is specific to the human TACC2 protein. |
Species Cross Reactivity | human - Not yet tested in other species |
Positive Controls | 293T | A431 | H1299 | HeLaS3 | HepG2 | Molt-4 | Raji |
Target | TACC2 |
Predicted Target Size(KDa) | 119.38 |
Cellular Localization | Cytoplasm | Nucleus | Centrosome |
Form Supplied | Liquid |
Concentration | 0.28 mg/ml |
Purification | Purified by antigen-affinity chromatography. |
Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage Instruction | Keep as concentrated solution. Aliquot and store at -20¨¬C or below. Avoid multiple freeze-thaw cycles. |
Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX110516 WB ImageSample(30 ug whole cell lysate)A:H12997.5% SDS PAGEGTX110516 diluted at 1:1000GTX110516 IHC ImageImmunohistochemical analysis of paraffin-embedded Cal27 xenograft, using TACC2(GTX110516) antibody at 1:100 dilution.Print:Print