Catalog Number | GTX101475 |
Product Name | UAP56 antibody |
Full Name | HLA-B associated transcript 1 |
Product Description | Rabbit polyclonal antibody to UAP56 (HLA-B associated transcript 1) |
Synonyms | D6S81E | DDX39B | UAP56 |
Background | This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq] |
Clonality | Polyclonal |
Host | Rabbit |
Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 274 of UAP56 |
Antigen Species | Human |
Tested Applications | WB,IHC-P,IF. The usefulness of this product in other applications has not been determined. |
Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000£¬IHC-P: 1:100-1:250£¬IF:1:100-1:200. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
Specificity | This antibody is specific to the Human UAP56 protein. |
Species Cross Reactivity | Human - Not yet tested in other species |
Positive Controls | 293T | A431 | H1299 | HeLa | HepG2 |
Target | UAP56 |
Predicted Target Size(KDa) | 49 |
Cellular Localization | Nucleus |
Form Supplied | Liquid |
Concentration | 0.43 mg/ml |
Purification | Purified by antigen-affinity chromatography. |
Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage Instruction | Keep as concentrated solution. Aliquot and store at -20¨¬C or below. Avoid multiple freeze-thaw cycles. |
Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX101475 WB ImageSample (30 ug of whole cell lysate) A: 293T 10% SDS PAGE GTX101475 diluted at 1:1000 GTX101475 IHC ImageImmunohistochemical analysis of paraffin-embedded A549 xenograft , using UAP56(GTX101475) antibody at 1:100 dilution.Print:Print