Catalog Number | GTX104676 |
Product Name | UBC3B antibody |
Full Name | ubiquitin-conjugating enzyme E2R 2 |
Product Description | Rabbit polyclonal antibody to UBC3B (ubiquitin-conjugating enzyme E2R 2) |
Synonyms | CDC34B | FLJ20419 | MGC10481 | UBC3B |
Background | Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq] |
Clonality | Polyclonal |
Host | Rabbit |
Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 14 of Human UBC3B |
Antigen Species | Human |
Tested Applications | Dot Blot |
Application Note | Further validation in progress. |
Specificity | This antibody is specific to the peptide antigen from UBC3B . |
Species Cross Reactivity | Human - Not yet tested in other species |
Positive Controls | Synthetic peptide: 1:8,000 |
Target | UBC3B |
Predicted Target Size(KDa) | 27.17 |
Form Supplied | Liquid |
Concentration | 8.65 mg/ml |
Purification | Affinity purified by Protein A. |
Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage Instruction | Keep as concentrated solution. Aliquot and store at -20¨¬C or below. Avoid multiple freeze-thaw cycles. |
Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |