Catalog Number | GTX108010 |
Product Name | VAM1 antibody |
Full Name | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
Product Description | Rabbit polyclonal antibody to VAM1 (membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)) |
Synonyms | PALS2 | VAM-1 | VAM1 | p55T |
Background | Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM] |
Clonality | Polyclonal |
Host | Rabbit |
Immunogen | Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 14 of VAM1 |
Antigen Species | Human |
Tested Applications | WB. The usefulness of this product in other applications has not been determined. |
Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
Specificity | This antibody is specific to the Human VAM1 protein. |
Species Cross Reactivity | Human - Not yet tested in other species |
Positive Controls | A549 | HeLa | Jurkat | NT2D1 |
Target | VAM1 |
Predicted Target Size(KDa) | 61.13 |
Cellular Localization | Membrane; Peripheral membrane protein |
Form Supplied | Liquid |
Concentration | 1 mg/ml |
Purification | Purified by antigen-affinity chromatography. |
Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage Instruction | Keep as concentrated solution. Aliquot and store at -20¨¬C or below. Avoid multiple freeze-thaw cycles. |
Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX108010 WB ImageSample (30 ug of whole cell lysate) A: NT2D1 7.5% SDS PAGE GTX108010 diluted at 1:1000 Print:Print