Catalog Number | GTX111477 |
Product Name | ZAK antibody |
Product Description | Rabbit polyclonal antibody to ZAK |
Synonyms | AZK | MLK7 | MLT | MLTK | MRK | mlklak |
Background | This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] |
Clonality | Polyclonal |
Host | Rabbit |
Immunogen | Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 229 of ZAK |
Antigen Species | human |
Tested Applications | WB and IF. The usefulness of this product in other applications has not been determined. |
Application Note | Suggested starting dilutions are as follows. WB: 1:500-1:3000,IF:1:100-1:200. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user. |
Specificity | This antibody is specific to the Human ZAK protein. |
Species Cross Reactivity | Human - Not yet tested in other species |
Positive Controls | 293T | A431 | H1299 | HeLa | HepG2 | Molt-4 | Raji |
Target | ZAK |
Predicted Target Size(KDa) | 91.17 |
Cellular Localization | Cytoplasm | Nucleus |
Form Supplied | Liquid |
Concentration | 1 mg/ml |
Purification | Purified by antigen-affinity chromatography. |
Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage Instruction | Keep as concentrated solution. Aliquot and store at -20¨¬C or below. Avoid multiple freeze-thaw cycles. |
Notes | For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. |
Image:GTX111477 WB ImageSample (30 ug of whole cell lysate) A: Molt-4 (GTX27912) 7.5% SDS PAGE GTX111477 diluted at 1:1000 GTX111477 IF ImageImmunofluorescence analysis of A431, using ZAK(GTX111477) antibody at 1:200 dilution.Print:Print